THE POWER OF THE BIOLOGY
Advanced Healing Solutions
ANNECY LIFE SURGERY 2023 
9th Annecy Live Surgery International Shoulder Advanced Course
08 June 2023 France
9th Annecy Live Surgery International Shoulder Advanced Course is an esteemed event that brings together a renowned international faculty, industry support, and a focus on delivering high-quality education.
The course aims to showcase the most up-to-date techniques in shoulder surgery through 35 live surgeries. Participants will have the opportunity to observe and learn from the best experts as they navigate various situations and challenges, all while being expertly moderated.
The event highlights the state-of-the-art advancements in shoulder surgery and emphasizes the real-time reactions of top surgeons in the face of difficulties. Additionally, the course utilizes 3D modeling of the shoulder to enhance understanding, and augmented reality technology will further enhance the learning experience.
The Annecy Live Surgery Course fosters interaction between the participants, scientific committee, moderators, and operating surgeons, providing an ideal platform for learning from concrete and complex cases. The ultimate goal of the course is to facilitate progress in participants' practices for the benefit and well-being of patients, always remaining at the forefront of their concerns.
Redefining Biological Healing in Rotator Cuff
Changing the course of rotator cuff progression
The REGENETEN Bioinductive Implant supports the body’s natural healing response to promote new tendon-like tissue growth and change the course of tear progression.1, 2, 9–11 Derived from highly purified bovine Achilles tendon, it creates an environment that is conducive to healing.1, 2, 9, 27
Open-architecture, now open to even greater possibilities
The unique open-architecture design of HEALICOIL anchors reduces the amount of implanted material in the shoulder compared to traditional, solid-core anchors.28
No other biocomposite can do this, a unique formulation of proven materials
Effective absorption and bone replacement in 24 months.6–8* REGENESORB material is designed to provide a jump start in bone healing and formation.
Advanced Healing Solutions
Instability Excellence
Citations
1. Bokor DJ, Sonnabend D, Deady L, et al. Evidence of healing of partial-thickness rotator cu tears following arthroscopic augmentation with a collagen implant: a 2-year MRI follow-up. Muscles, Ligaments Tendons J 2016;6(1):16-25.
2. Schlegel TF, Abrams JS, Bushnell BD, Brock JL, Ho CP. Radiologic and clinical evaluation of a bioabsorbable collagen implant to treat partial-thickness tears: a prospective multicenter study. J Shoulder Elbow Surg. 2018 27(2):242-251.
3. Bokor DJ, Sonnabend D, Deady L, et al. Preliminary investigation of a biological augmentation of rotator cu repairs using a collagen implant: a 2-year MRI follow-up. Muscles, Ligaments Tendons J 2015;5(3):144-150.
4. Chahla J, Liu JN, Manderle B, et al. Bony Ingrowth of Coil-Type Open-Architecture Anchors Compared With Screw-Type PEEK Anchors for the Medial Row in Rotator Cu Repair: A Randomized Controlled Trial. Arthroscopy. 2020;36(4):952-961.
5. Clark TR, Guerrero EM, Song A, O’Brien MJ, Savoie FH. Do vented suture anchors make a dierence in rotator cu healing. Ann Sports Med Res. 2016;3:1068.
6. Vonhoegen J, John D, Hägermann C. Osteoconductive resorption characteristics of a novel biocomposite suture anchor material in rotator cuff repair. Orthop Traumatol Surg Res. 2019;14(1):12.
7. Smith+Nephew 2010. Micro-CT and histological evaluation of specimens from resorbable screw study (RS-II / OM1-08) 24-month post-implantation. Internal Report WRP-TE045-700-08.
8. Smith+Nephew 2016. HEALICOIL REGENESORB Suture Anchor – a study to assess implant replacement by bone over a 2 year period. NCS248.
9. Van Kampen C, Arnockzky S, Parks P et al. Tissue-engineered augmentation of a rotator cuff tendon using a reconstituted collagen scaffold: A histological evaluation in sheep. MLTJ. 2013;3:229-235.
10. Bokor DJ, Sonnabend DH, Deady L, et al. Healing of partial-thickness rotator cuff tears following arthroscopic augmentation with a highly porous collagen implant: a 5-year clinical and MRI follow-up. Muscles, Ligaments Tendons J. 2019;9(3):338-347.
11. McElvany MD, McGoldrick E, Gee AO, Neradilek MB, Matsen FA, 3rd. Rotator cuff repair: published evidence on factors associated with repair integrity and clinical outcome. Am J Sports Med. 2015;43(2):491-500.
12. Material and Structural Testing Core, Mayo Clinic 2019. Proof-of-concept Finite Element Modelling of Effect of Tissue Induction on Rotator Cuff Tears. Internal Report. EO/SPM/REGENTEN/001/V1.
13. Arnoczky SP, Bishai SK, Schofield B, et al. Histologic Evaluation of Biopsy Specimens Obtained After Rotator Cuff Repair Augmented With a Highly Porous Collagen Implant. Arthroscopy. 2017;33(2):278-283.
14. Smith+Nephew 2020. HEALICOIL KNOTLESS claims testing, less suture displacement after postoperative cyclic loading 15009719 A.
15. Smith+Nephew 2020. HEALICOIL KNOTLESS claims testing, proven internal locking plug mechanism 15009718 A.
16. Smith+Nephew 2020. HEALICOIL KNOTLESS claims testing, less foreign material than competitor 15009720 A.
17. Kim JH, Kim YS, Park I, Lee HJ, Han SY, Jung S, SHin SJ. A Comparison of Open-Construct PEEK Suture Anchor and Non-Vented Biocomposite Suture Anchor in Arthroscopic Rotator Cuff Repair: A Prospective Randomized Clincial Trial. Arthroscopy. 2020, 36 (2): 389-396.
18. Constantino, Friedman. Synthetic Bone Graft Subsitutes. Otolaryngol Clin North Am. 1994 27(5):1037-1074.
19. Walsh WR, Morberg P, Yu Y, et al. Response of a calcium sulfate bone graft substitute in a confined cancellous defect. Clin Orthop Relat Res. 2003(406):228-236.
20. Calori GM, Mazza E, Colombo M, Ripamonti C. The use of bone-graft substitutes in large bone defects: Any specific needs? Injury. 2011;42(2):S56-S63.
21. Arai E, Nakashima H, Tsukushi S, et al. Regenerating the fibula with beta-tricalcium phosphate minimizes morbidity after fibula resection. Clin Orthop Relat Res. 2005(431):233-237.
22. Gaasbeek RD, Toonen HG, van Heerwaarden RJ, Buma P. Mechanism of bone incorporation of beta-TCP bone substitute in open wedge tibial osteotomy in patients. Biomaterials. 2005;26(33):6713-6719.
23. Park K, Skidmore S, Hadar J, et al. Injectable, long-acting PLGA formulations: Analyzing PLGA and understanding microparticle formation. J Control Release. 2019;304:125-134.
24. Chu C-C. Section IV:44, Biodegradable Polymeric Biomaterials: An Updated Overview. In: The Biomedical Engineering Handbook. Bronzino JD Ed. CRC Press.; 1995.
25. Smith+Nephew 2019 Verification, Microraptor Knotless Real Time Degredation. Revision B. Internal Report 15007134.
26. Smith and Nephew 2019. Verification, Microraptor Knotless Accelerated Degredation. Internal Report 15007045.
27. Smith + Nephew 2020 REGENETEN Collagen Implant Physical Characteristics. Internal Report
28. Smith+Nephew 2021. Technical Report, HEALICOIL Implant Volume Comparison. Internal Report. 15010823 Rev A
29. Allison DC, Lindberg AW, Mirzayan R, Samimi B, Menendez LR. A Comparison of Mineral Bone Graft Substitutes for Bone Defects. US Oncology and Hematolog. 2011.
30. Ogose A, Kondo N, Umezu H, et al. Histological assessment in grafts of highly purified beta-tricalcium phosphate (OSferions) in human bones.
* Demonstrated clinically and in vivo