Oxidized Zirconium

OXINIUM Oxidized Zirconium has several key properties that differentiate it from other bearing materials, with each material property contributing to the performance of OXINIUM Technology implants.
OXINIUM Technology has demonstrated the ability to:

  • Reduce wear (versus cobalt chrome)5,6
  • Deliver the wear resistance of ceramic without the concern of phase transformation and brittle fracture2,7,19,20
  • Provide corrosion resistance better than cobalt-chrome or ceramic8,9
  • Go beyond basic biocompatibility – OXINIUM Technology may also have a reduced impact on the inflammatory response, as demonstrated by lower pro-inflammatory cytokine expression in cells exposed to OXINIUM Technology (versus CoCrMo and Ti alloy)*10,21

The end result is a material that has demonstrated the lowest risk of revision in multiple national and regional hip registries,14-17 and the ability to significantly reduce the risk of revision caused by aseptic loosening and infection, versus cobalt chrome implants of the same design in total knee replacement.22

Product Features


Medical Education

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*The results of in vitro wear simulation testing have not been proven to quantitatively predict clinical wear performance.

  1. 2005 ASM International Engineering Materials Achievement Award.
  2. Hunter G, Dickinson J, Herb B, et al. Creation of oxidized zirconium orthopaedic implants. Journal of ASTM International. 2005;2:1-14.
  3. Long M, Riester L, Hunter G. Nano-hardness Measurements of Oxidized Zr-2.5Nb and Various Orthopaedic Materials. Abstract presented at: 24th Annual Meeting of the Society for Biomaterials. April 22-26, 1998, San Diego, California.
  4. Parikh A, Hill P, Hines G, Pawar V. Wear of conventional and highly crosslinked polyethylene liners during simulated fast walking/jogging. Poster presented at: 55th Annual Meeting of the Orthopaedic Research Society, 2009. Poster no. 2340.
  5. Parikh A, Hill P, Pawar V, Sprague J. Long-term Simulator Wear Performance of an Advanced Bearing Technology for THA. Poster presented at: 2013 Annual Meeting of the Orthopaedic Research Society. Poster no. 1028.
  6. Papannagari R, Hines G, Sprague J, Morrison M. Long-term wear performance of an advanced bearing technology for TKA. Poster presented at: 2011 Annual Meeting of the Orthopaedic Research Society. Poster no. 1141.
  7. Smith+Nephew 2010. OR-10-155.
  8. Aldinger P, Williams T, Woodard E. Accelerated Fretting Corrosion Testing of Zirconia Toughened Alumina Composite Ceramic and a New Composition of Ceramicised Metal Femoral Heads. Poster presented at: 2017 Annual Meeting of the Orthopaedic Research Society. Poster no. 1037.
  9. Smith+Nephew 2016. OR-16-127.
  10. Dalal A, Pawar V, McAllister K, Weaver C, Hallab NJ. Orthopedic implant cobalt-alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium alloy-based particles in vitro, in human osteoblasts, fibroblasts, and macrophages. J Biomed Mater Res Part A. 2012;100A:2147-2158
  11. ASTM International Standard Specification for Wrought Zirconium-2.5 Niobium Alloy for Surgical Implant Applications (UNS R60901) Designation: F 2384 – 10.
  12. ASTM International Standard Specification for Cobalt-28 Chromium-6 Molybdenum Alloy Castings and Casting Alloy for Surgical Implants (UNS R30075): Designation: F 75 – 12
  13. ASTM International Standard Specification for Wrought Cobalt-28 Chromium-6 Molybdenum Alloys for Surgical Implants (UNS R31537, UNS R31538, and UNS R31539): Designation: F1537-20.
  14. Davis ET, Pagkalos J, Kopjar B. Bearing surface and survival of cementless and hybrid total hip arthroplasty in the National Joint Registry of England, Wales, Northern Ireland and the Isle of Man. Journal of Bone Joint Surgery. 2020;5(2):pe0075.
  15. Peters RM, Van Steenbergen LN, Stevens M, et al. The effect of bearing type on the outcome of total hip arthroplasty. Acta Orthopaedica. 2018; 89(2):163-169.
  16. Atrey A, Ancarani C, Fitch D, Bordini B. Impact of bearing couple on long-term component survivorship for primary cementless total hip replacement in a large arthroplasty registry. Poster Presented at: Canadian Orthopedic Association; June 20–23, 2018; Victoria, British Columbia, Canada.
  17. Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR). Hip, Knee & Shoulder Arthoplasty: 2022 Annual Report. Adelaide: AOA, 2022.
  18. Innocenti M, Matassi F, Carulli C, Nistri L, Civinni C. Oxidized zirconium femoral component for TKA: A follow-up note of a previous report at a minimum of 10 years. The Knee. 2014;21:858-861.
  19. Evidence Analysis Report EA/RECON/POLAR3/007/v1. 11th December 2020.
  20. Medel FJ, et al. 55th Annual Meeting of the Orthopaedic Research Society, 2009; Poster No. 2300.
  21. Hallab NJ, et al. Annual Meeting of the Orthopaedic Research Society (ORS), 2012. San Francisco, CA.
  22. National Joint Registry for England, Wales and Northern Ireland: Bespoke report for Genesis II/ Legion/ Journey II: Oxinium vs CoCr. 8 March 2022. Report available upon request.