Leave nothing to chance

Manage the incision. Manage the outcome. Leave nothing to chance with PICO◊ Single Use Negative Pressure Wound Therapy.

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PICO sNPWT is the only NPWT system supported by NICE for prophylactic treatment of SSIs across a range of surgical specialisms1 – based on up-to-date meta-analysis, reinforced by independent clinical data and real-world evidence.1–6

Discover the NEW NICE Medical Technologies Guidance (MTG43)

NICE (National Institute for Health and Care Excellence) offers evidence-based recommendations for the health and social care sector. These are developed by independent committees made up of professionals and lay members, with input from relevant stakeholders. NICE guidance helps NHS professionals make informed, cost-effective, and consistent decisions regarding the adoption of new medical technologies. It also promotes innovation, supports transformation, and enhances healthcare delivery.1

In 2024, NICE reviewed the "Medical Technology Guidance 43" (Download NICE MTG43 PDF), which focuses on PICO negative pressure wound dressings for closed surgical incisions. The guidance highlights that Smith+Nephew’s PICO sNPWT delivers better clinical outcomes compared to standard dressings for patients at high risk of surgical site infections (SSIs), while maintaining similar overall costs.

As a result, it has reconfirmed its guidance following a review of an additional 28 papers published.2

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NICE Recommendations

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Learn about NICE guidelines

Lancet publication

Incisional negative pressure wound therapy (iNPWT) for reducing the risk of surgical site infection: an up-to-date meta-analysis and trial sequential analysis

This meta-analysis confidently showed that single use iNPWT reduces the risk of SSI irrespective of specific surgical specialties, whilst trial sequential analysis demonstratedthe robustness of this evidence. Additionally, no significant differences were observed between -80mmHg and -125mmHg devices.


Read highlights from the Lancet publication

Address the current burden of SSI

Healthcare-associated infections (HAI) are an important public health problem.High-income countries have a lower incidence of SSI; however, in Europe and the USA, SSI is the second most common type of HAI.7

  • Low and middle income countries - SSI incidence: 1/3 of surgical patient develop SSI. 7
  • High income countries - SSI incidence:
    - US : 2-5% of patients undergoing inpatient surgery 7
    - Europe : varied from 0.6% in knee prosthesis surgery to 9.5% in open colon surgery, depending on the type of surgical procedure. 8

Although SSIs carry a substantial burden to health-care systems and service payers worldwide in terms of patient morbidity, mortality, and additional costs, SSIs are among the most preventable health-care-associated infections 11.

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Reduce SSI odds by changing your practice!

PICO Single Use Negative Pressure Wound Therapy System (sNPWT) help prevent surgical site complications in high-risk patients with surgically closed incisions. 12,13

A systematic literature review and meta-analysis of 29 studies involving 5.614 patients undergoing surgery compared prophylactic use of PICO sNPWT with standard care showed:12,13

Compared with standard care, prophylactic use of PICO sNPWT in patients with surgical closed incisions, resulted in: 13

Leave nothing to chance – Contact us today

To learn more or for a PICO demonstration, simply fill out the form below. Our team is here to provide you with the support and information you need.

Citations
  1. National Institute for Health and Care Excellence. PICO negative pressure wound dressings for closed surgical incisions (MTG43). 2019. Available from:
  2. National Institute for Health and Care Excellence. MTG review decision document. 2024.
  3. Groenen H, et al. Incisional negative pressure wound therapy for the prevention of surgical site infection: an up-to-date meta-analysis and trial sequential analysis Lancet 2023; 62:102105.
  4. National Institute for Health and Care Excellence. University Hospitals Bristol Implementation of PICO incision Management Negative Pressure Wound therapy in the high-risk Cardiac Surgery Patient Group.
  5. Fleming CA, et al. Routine use of PICO dressings may reduce overall groin wound complication rates following peripheral vascular surgery J Hosp Infect 2018; 9(1):75–80.
  6. Karlakki SL, et al. Incisional negative pressure wound therapy dressings (iNPWTd) in routine primary hip and knee arthroplasties: A randomised controlled trial Bone Joint Res 2016;5(8):328–37.
  7. Gülseren Maraş, et al. Surgical Site Infections: Prevalence, Economic Burden, and New Preventive Recommendations. Exploratory Research and Hypothesis in Medicine 2023;8(4):366-371 doi: 10.14218/ERHM.2023.00010
  8. European Centre for Disease Prevention and Control Healthcare-associated infections: surgical site infections - Annual Epidemiological Report for 2018–2020
  9. Heinz J, Walshaw J, Kwan JY, Long J, Carradice D, Totty J, Kontouli KM, Lainas P, Hitchman L, Smith G, Huo B, Guadalajara H, Garcia-Olmo D, Sharma D, Biyani CS, Tomlinson J, Loubani M, Galli R, Lathan R, Chetter I, Yiasemidou M. PRESS survey: PREvention of surgical site infection-a global pan-specialty survey of practice protocol. Front Surg. 2023 Sep 25;10:1251444. doi: 10.3389/fsurg.2023.1251444. PMID: 37818209; PMCID: PMC10560728.
  10. Guest JF, et al. BMJ Open 2023;13:e076735. doi:10.1136/bmjopen-2023-076735
  11. Allegranzi B, Bischoff P, de Jonge S, Kubilay NZ, Zayed B, Gomes SM, Abbas M, Atema JJ, Gans S, van Rijen M, Boermeester MA, Egger M, Kluytmans J, Pittet D, Solomkin JS; WHO Guidelines
  12. Saunders C, Nherera LM, Horner A, Trueman P. Single-use negative-pressure wound therapy versus conventional dressings for closed surgical incisions: systematic literature review and meta-analysis. BJS Open. 2021;5(1):1–8.
  13. Nherera LM, Saunders C, Verma S, Trueman P, Fatoye F. Single-use negative pressure wound therapy reduces costs in closed surgical incisions: UK and US economic evaluation. J Wound Care. 2021;30(Sup5):S23–S31.

PICO Social Media Campaign References:

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  1. NHS. NWCSP Surgical Wound Complications Recommendations [November 2024].
  2. NHS England. https://gettingitrightfirsttime.co.uk/wp-content/ uploads/2017/08/SSI-Report-GIRFT-APRIL19e-FINAL.pdf [November 2024].
  3. NICE. https://www.nice.org.uk/guidance/mtg43/evidence/review-report-february-2024-pdf-13314467630 [November 2024].
  4. Saunders C, et al. BJS Open 2021;5(1):zraa003.

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  1. NICE. https://www.nice.org.uk/guidance/mtg43/evidence/review-report-february-2024-pdf-13314467630 [November 2024].
  2. NHS England. https://gettingitrightfirsttime.co.uk/wp-content/ uploads/2017/08/SSI-Report-GIRFT-APRIL19e-FINAL.pdf [November 2024].
  3. Saunders C, et al. BJS Open 2021;5(1):zraa003.
  4. NICE. https://www.nice.org.uk/sharedlearning/university- hospitals-bristol-implementation-of-pico-incision-management- negative-pressure-wound-therapy-in-the-high-risk-cardiac- surgery-patient-group#methods/ [Accessed November 2024].
  5. Fleming CA, et al. J Hosp Infect 2018; 9(1):75–80.
  6. Karlakki SL, et al. Bone Joint Res 2016; 5(8):328–37.

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  1. Groenen H, Jalalzadeh H, Buis DR, et al. eClinicalMedicine (part of The Lancet group). 2023;62:102105.

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  1. Groenen H, Jalalzadeh H, Buis DR, et al. eClinicalMedicine (part of The Lancet group). 2023;62:102105.

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