17 October 2018

Two new studies demonstrate INTERTAN™ Intertrochanteric Antegrade Nail improves patient outcomes and lowers healthcare costs when treating hip fractures

Smith & Nephew (LSE: SN, NYSE: SNN), the global medical technology business, today announced at the Orthopaedic Trauma Association Annual Meeting in Orlando, FL USA two new studies showing positive clinical results and cost savings through using its INTERTAN Intertrochanteric Antegrade Nail.

Patients recovering from a hip fracture often deal with various complications, including decline in mobility and daily living activities, and reduced ability to walk following fracture union. More than 6% will require reoperation due to complications and approximately 1 in 4 patients over the age of 65 die within 12 months of fracture.1,2,3

In a meta-analysis published in Rheumatology and Orthopedic Medicine, the INTERTAN implant, which uses the Smith & Nephew proprietary “Integrated Compression Screw”, was compared to other intertrochanteric nails using a customary “single screw”. The results showed that INTERTAN significantly reduced the risk of implant related failures by 81% (p<0.00001) and revision surgery by 65% (p<0.0001) when compared to single screw nails.4

According to a further study, published in Journal of Orthopaedic Surgery and Research,  the improved clinical outcomes from the meta-analysis also led to a cost savings of $2700 USD per patient when using the INTERTAN nail compared to single screw nails.5

“Hip fractures and their sequelae in elderly patients can be debilitating, and potentially life threatening, and contribute a significant portion to overall health care expenditure. These new studies demonstrate that the Integrated Compression Screw used in the INTERTAN nail not only improved the clinical outcomes for these patients studied, but also reduced the cost to the overall health economic system by reducing the revision rates, compared to those that have been demonstrated in prior studies,” commented J. Tracy Watson MD, Orthopaedic Traumatologist,  Phoenix, Arizona and co-author for both papers. 

“Smith & Nephew is dedicated to developing products that will improve patient lives. The INTERTAN nail is a prime example of the type of game-changing technology we at Smith & Nephew strive to create. These two publications show how true innovation can both make clinical improvement and provide economic benefits,” said Andy Weymann MD, Chief Medical Officer, Smith & Nephew.

For more information on the INTERTAN nail, please visit us at the Orthopaedic Trauma Association Annual Meeting, Booth #805 or online at hipfx.com.



Dave Snyder
+1 (978) 749-1440
Smith & Nephew plc 

Charles Reynolds
+44 (0) 1923 477314
Smith & Nephew plc

About Smith & Nephew

Smith & Nephew is a global medical technology business dedicated to helping healthcare professionals improve people's lives. With leadership positions in Orthopaedic Reconstruction, Advanced Wound Management, Sports Medicine and Trauma & Extremities, Smith & Nephew has around 15,000 employees and a presence in more than 100 countries. Annual sales in 2017 were almost $4.8 billion. Smith & Nephew is a member of the FTSE100 (LSE:SN, NYSE:SNN).

For more information about Smith & Nephew, please visit our website www.smith-nephew.com, follow @SmithNephewplc on Twitter or visit SmithNephewplc on Facebook.com.


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1. American Academy of Orthopaedic Surgeons. Hip fractures in seniors: a call for health system reform. Position Statement 1144. Rosemont, IL: 1999.
2. Mundi S et al. Similar mortality rates in hip fracture patients over the past 31 years: A systematic review of RCTs. Acta Orthopaedica 2014; 85(1): 54-59.
3. Bentler SE, Liu L, Obrizan M, Cook EA, Wright KB, Geweke JF, et al. The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am. J Epidemiol. 2009 Nov 15;170(10):1290-9. doi: 10.1093/aje/kwp266.
4.Nherera LM, Trueman P, Horner A, Johnstone AJ, Watson JT. A meta-analysis of integrated compression screw compared to single screw nails using a single lag screw or single helical blade screw for intertrochanteric hip fractures. Rheumatol Orthop Med 2018; 3(4): 1-10. doi: 10.15761/ROM.1000156
5. Nherera LM, Trueman P, Horner A, Johnston AJ, Watson JT, Fatoye FA. Comparing the costs and outcomes of an integrated twin compression screw (ITCS) nail with standard of care using a single lag screw or a single helical blade cephalomedullary nail in patients with intertrochanteric hip fractures. Journal of Orthopedic Surgery and Research (2018) 13:217. doi: 10.1186/s12018-018-0923-x