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Biobrane^ Instructions for Use

This information is intended for Healthcare Professionals only.

Biobrane reduces patient pain and decreases healing time

 

Initial adherence results from the fibrin in a clean wound surface preferentially bonding to the collagen surface of Biobrane. Secondary stronger adherence results from physical entrapment by fibrin and tissue ingrowth into the nylon fabric.

 

APPLICATION

Biobrane application
  • Application should be to freshly debrided or excised, or meshed autograft wounds containing less than 10 5 bacteria/g tissue.

Caution: The debridement or excision must be done thoroughly to remove all coagulum or eschar. Biobrane will not adhere to dead tissue, and any remaining necrotic tissue may cause infection.

  • Establish haemostasis prior to application of Biobrane.

 

  • Apply FABRIC (DULL) SIDE DOWN, wrinkle-free against the wound surface with slight tension.

NOTE: If less secondary adherence is desired, i.e., deeper donor sites or widely meshed autografts, Biobrane-L is recommended.

  • Under slight tension immobilize the Biobrane using staples, tape, sutures, or skin closure strips and wrap area with a dry gauze dressing or other stenting device to hold the Biobrane firmly in contact with the wound surface for 24 to 36 hours.

 

 

 

NURSING/PATIENT INSTRUCTIONS

24 hours post application

  • Do not remove the outer dressing.
  • Do not get the dressing wet.
  • Do not move the covered area more than necessary.

Biobrane

 

 

24 to 36 hours post application

Remove the outer dressing down to the Biobrane and observe for the following:

  • If Biobrane is adherent and no fluid accumulation is present, rewrap with gauze for protection.
  • If Biobrane is loose, but the underlying tissue is still viable, aspirate or roll out any non-purulent fluid collection, rewrap with a gauze dressing and observe in 24 hours for adherence.
  • If Biobrane is loose and there is purulent drainage underneath, remove purulent non-adherent areas and use conventional topical antimicrobial therapy to reduce bacterial contamination to safe levels.

 

 

 

48 to 72 hours post application

  • Remove the outer dressing down to the Biobrane and check for adherence. If Biobrane is adherent, the outer dressing need not be reapplied. If non-adherent, treat as reference above.
  • Observe the covered wound daily for bubbles and purulence and treat as referenced above. Biobrane should be removed from areas of the wound with signs of infection.
  • Remove staples, tape, sutures, or skin closure strips 3 to 4 days post application or when adherence is achieved.
  • Once the Biobrane is adherent, patients can be bathed according to standard burn unit protocols.
  • Once Biobrane is adherent, motion of the burned area can be initiated.

 

 

REMOVAL

  • Remove the Biobrane when the tissue underneath is healed typically 7 to 14 days. Appearance of Biobrane is dry, loose in spots and patient may report itching.
  • If edges are loose, they can be trimmed away until the entire partial thickness wound has healed.
  • Remove by starting at one corner and pull gently. Biobrane will peel off healed tissue relatively easily. The application of a petroleum based ointment or soaking prior to removal facilitates the removal process.

Caution: If bleeding occurs, or if patient complains of excessive pain, stop and wait 1 to 2 additional days. Forced removal may result in wound re-injury. If Biobrane becomes adherent to a partial thickness wound which has progressed to a full thickness wound, it should be removed in the operating room prior to autografting.

Warning:In rare instances, allergic reactions to Biobrane have been reported. If a patient shows evidence of allergic reaction, Biobrane should be removed and its use discontinued.

 

References >

 

 

^ Registered trademark of Bertek Pharmaceuticals Inc.