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Iodosorb* Simple Science

This information is intended for Healthcare Professionals only.


Cadexomer iodine

Iodosorb is a uniquely formulated Cadexomer matrix formed into spherical, highly absorbent microbeads containing 0.9% elemental iodine.


The Cadexomer is a 3D cross - linked polysaccharide starch matrix. The 0.9% iodine is physically bound to the cadexomer matrix and is only released when it is required.



Cadexomer Iodine: The Mode of Action


0.9% Iodine immobilised in cadexomer is slowly released from the cadexomer to an iodine free environment in the presence of exudate (the wound)


The Iodine (I 2) will move across a concentration gradient until an equilibrium is established between Iodosorb and the wound bed.


Once in the wound bed, the I 2 will convert to I- as it kills

micro-organisms. When all the I 2 has been converted to I- there will be a noticeable colour change which will indicate that it is time to change Iodosorb.

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Wound fluid and exudate are absorbed into the cadexomer beads of the Cadexomer Iodine, allowing the iodine to be released slowly. Please refer to the animation below.


When Iodosorb is applied to the wound surface, exudate, pus and debris are absorbed into the cadexomer beads. The beads will swell resulting in the formation of a demonstrable gel.


The presence of exudate and the consequent swelling of the beads results in the cross - linked bonds of the cadexomer matrix breaking and the iodine being released into the surrounding wound environment. When the iodine is released, the amount of iodine released will be to a level such that the concentration of iodine in the dressing and the wound environment reach an equilibrium. The equilibrium will remain and no further iodine will be released until the balance is disturbed.


Once the iodine in the surrounding wound environment has been depleted, more will be released from the product until the equilibrium is reached again and will remain until disturbed. This process will continue until all the 0.9% iodine within the product has been exhausted. The conversion of iodine is also associated with a colour change from orangey brown to white. Therefore once all the iodine has been converted and utilised, the Iodosorb will appear white in colour. At this point it is time to make a dressing change.



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