‡ In these countries please contact our distributor

I - Infection

The products used in the T.I.M.E. clinical decision support tool may vary in different markets.  Not all products referred to may be approved for use or available in all markets.  Please consult your local Smith & Nephew representative for further details on products available in your market. 


Aim to achieve non-inflamed, non-infected wounds

Identifying and addressing wound infection, to reduce bacterial burden and dampen the inflammatory response, is essential to promote wound healing and correctly inform antibiotics use1.


When to act on infection2



Think – Contamination: unless compromised, patient will respond and destroy bacteria.
Think – Colonisation: limited, non-critical proliferation of microbes that will not affect wound progression.
Act – Localised: deeper presence in the wound tissue, but currently contained in one location, system or structure.
Act – Spreading: infection present in surrounding tissue with signs and symptoms beyond the wound border, potentially into deep tissue, muscle, fascia organs or body cavities.
Act – Systemic: microorganisms spread through the vascular or lymphatic systems and can affect the whole body.


  Disrupt: Effective bacterial assessment and identification is essential to initiate the correct treatment.



Using our T.I.M.E. clinical decision support tool

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Local infection: treat with a dressing containing an antimicrobial*

ACTICOAT Nanocrystalline Silver Dressings
IODOFLEXCadexomer Iodine Pad
IODOSORBCadexomer Iodine Ointment, Gel or Powder



Spreading system infection: treat with an antimicrobial and appropriate systemic antibiotics*

ACTICOAT Nanocrystalline Silver Dressings
IODOFLEXCadexomer Iodine Pad
IODOSORBCadexomer Iodine Ointment, Gel or Powder


  Next step > Evaluate the effectiveness of treatment and progression towards your wound management goal.


For additional product information or ordering instructions, arrange a call from a Smith & Nephew representative.


Helping you get CLOSER TO ZERO human and economic cost of wounds.


A healthcare professional must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. Smith & Nephew does not dispense medical advice and recommends that healthcare professionals be trained in the use of any particular product before using it on patients.


For detailed product information, including indications for use, contraindications, effects, precautions, warnings, and important safety information, please consult the Instructions for Use (IFU) prior to use.

Where a dressing is used on an infected wound, the infection should be inspected and treated as per the local clinical protocol.

*Use appropriate secondary dressings according to your local protocol. 



1) Schultz G, et al. (2005) Wound healing and T.I.M.E.; new concepts and scientific applications. Wound Repair Regen. 13, S1–11.
2) International Wound Infection Institute (IWII). Wound infection in clinical practice. Wounds International 2016.