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ALLEVYN◊ Ag

Advanced Foam Wound Dressings

ALLEVYN Ag

Product Information

ALLEVYN AG

Wound infection can significantly compromise patient wellbeing and place heavy burdens on healthcare economies. The ALLEVYN Ag dressings have been designed to combine the essential qualities of the ALLEVYN range with the added antimicrobial activity of silver.

The unique tri-layer construction of the dressings enable optimal fluid handling to support moist wound healing1 and the addition of silver to the foam pad provides a broad spectrum bacterial kill in-vitro2,3. The dressings are comfortable for patients, conform to body contours and are easy to apply and remove4,5,6,7.

The ALLEVYN Ag range is available as:

ALLEVYN Ag AdhesiveALLEVYN Ag Adhesive

A highly absorbent8 secure antimicrobial foam dressing that is also available in a sacral shape for this area that is at high risk of contamination

ALLEVYN Ag Adhesive Size and Ordering Information

Size
 S&N Code
CartonNHS CodePIP Code
7.5cm x 7.5cm
66800073
10
ELA344 333-1352
10cm x 10cm
66800075
10
ELA345 333-1147
12.5cm x 12.5cm
66800078
10
ELA347 333-1154
17.5cm x 17.5cm
66800081 10
ELA350 333-1162
17cm x 17cm Sacrum 66800094 10 ELA349 333-1295
22cm x 22cm Sacrum
66000451
10
ELA352 333-1394

 

ALLEVYN Ag Non-AdhesiveALLEVYN Ag Non-Adhesive

A highly absorbent9 non-adherent10 antimicrobial foam dressing suitable for compromised skin that can be cut to suit the patient

ALLEVYN Ag Non-Adhesive Size and Ordering Information

Size
 S&N Code
CartonNHS CodePIP Code
5cm x 5cm
66800083
10
ELA343 333-1170
10cm x 10cm
66800086
10
ELA346 333-1188
15cm x 15cm
66800089
10
ELA348 333-1196
20cm x 20cm
66800091
10
ELA351 333-1212
10.5cm x 13.5cm Heel
66800098
10
ELA374 341-9397

 

ALLEVYN Ag GentleALLEVYN Ag Gentle

A highly absorbent11 antimicrobial foam dressing with a soft gel gentle adhesive to enable easy application6 under secondary retention including compression.

ALLEVYN Ag Gentle Size and Ordering Information

Size
 S&N Code
CartonNHS CodePIP Code
5cm x 5cm
66800464
10
ELA393 346-7511
10cm x 10cm
66800465
10
ELA394 346-7529
10cm x 20cm
66800466
10
ELA395 346-7537
15cm x 15cm
66800467
10
ELA396 346-7545
20cm x 20cm
66800468
10
ELA397 346-7552

 

ALLEVYN Ag Gentle BorderALLEVYN Ag Gentle Border

A highly absorbent12 antimicrobial foam dressing with a gentle silicone adhesive, the ideal one step dressing for use on fragile skin7.

ALLEVYN Ag Gentle Border Size and Ordering Information

Size
 S&N Code
CartonNHS CodePIP Code
7.5cm x 7.5cm
66800460
10
ELA398 346-7677
10cm x 10cm
66800461
10
ELA399 346-7685
12.5cm x 12.5cm
66800462
10
ELA400 346-7693
17.5cm x 17.5cm
66800463
10
ELA401 346-7701

All of the ALLEVYN Ag dressings combine the physical qualities of the ALLEVYN tri-layer construction with the antimicrobial activity of silver. Proven in-vitro against a broad spectrum of bacteria including antibiotic resistant bacteria such as Pseudomonas, Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin Resistant Enterococcus (VRE)2,3 the ALLEVYN Ag range provides a sustained action with antimicrobial properties remaining effective for up to 7 days in-vitro3,13,14.

The ALLEVYN Ag dressings are indicated for:

  • Shallow, granulating wounds
  • Chronic and acute exudative wounds
  • Full and partial thickness wounds such as pressure ulcers, leg ulcers and diabetic foot ulcers
  • Infected wounds
  • Malignant wounds
  • Surgical wounds
  • First and second degree burns
  • Donor sites
  • Fungating wounds

 

References

1. The clinical and physical properties of ALLEVYN Ag dressings and the moist wound environment
2. Data on File 0707052 – Antimicrobial activity of ALLEVYN Ag dressings against a broad spectrum of wound pathogens using a dynamic shake flask method. July (in-vitro)
3. Smith & Nephew Research Centre Report Ref: RR-WMP07330-10-03. The equivalence of the antimicrobial efficacies of the ALLEVYN Ag foam variants against key wound pathogens. Driffield K, Woodmansey E. Dates 25/03/2009 (in-vitro)
4. Harding KG, Bale S. A randomised clinical study to evaluate and compare the performance of ALLEVYN Adhesive and Tielle dressings in the management of exuding wounds in the community: Smith & Nephew healthcare.
5. Managing diabetic foot lesions with ALLEVYN Heel dressing , Watret L (2000) The Diabetic Foot, 3(1),21-22
6. Data on file report ref: 0711086 – Results from a 7 day volunteer trial evaluating ALLEVYN Gentle dressings in terms of pain on removal, dressing retention and other physical characteristics. A. Bond December 2007
7. Smith & Nephew Medical Ltd. Report Ref: HVT050 Results from an open, prospective, randomised, within volunteer comparison of Dakota and Mepilex Border, Palmer S., & Smith G. 4th December 2008
8. Data on File Reference 0702002, ALLEVYN Ag Adhesive dressing Physical Properties, Daubney L, February 2007 (in-vitro)
9. Data on File Reference 0702001, ALLEVYN Ag Non Adhesive – Physical Properties, L Daubney, February 2007 (in-vitro)
10. Comparing two dressings in the treatment of diabetic foot ulcers, Foster AVM et al (1994), J Wound Care, 3(5), 224-228
11. Smith & Nephew Medical Ltd. Report Ref: DS/08/107/R1b, ALLEVYN Ag Gentle Dressings Physical Properties, Carpenter S. November 2008 (in-vitro)
12. Smith and Nephew Medical Ltd. Report Ref: DS/08/098/R1b, ALLEVYN Ag Gentle Border Dressings Physical Properties, Carpenter S, November 2008 (in-vitro)
13. Data on File 0703014 – Antimicrobial activity of ALLLEVYN Ag Adhesive over 7 days. E. Woodmansey March 2007 (in-vitro)
14. Data on File 0703003 – Antimicrobial activity of ALLEVYN Ag Non-Adhesive over 7 days. E. Woodmansey March 2007 (in-vitro)
15. Avanzi R, Martinelli R, Accardi S, Giraudi C, Peroli P, Rowan S et al. Adhesive hydrocellular dressing vs. hydrocolloid dressing in the treatment of 2nd and 3rd degree pressure ulcers.
16. ALLEVYN Gentle – A 17 day wound healing study in full thickness wounds in minipigs, September 2007
17. ALLEVYN Gentle Border (Dakota) – A 17 day wound healing study in Full Thickness Wounds in Minipigs, October 2008
18. A human repeat insult patch test with adhesive materials. Inveresk Research International Report No. 3524, June 1986
19. Smith & Nephew Data on File Report Comparison of the Permeability of ALLEVYN Non-Adhesive standard and the new ALLEVYN Non-Adhesive written by David Foster and Ana Riel. February 2006 (in-vitro)
20. Smith & Nephew Wound Management, report ref: 070305, Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Gentle, ALLEVYN Gentle Border dressings with 7 day test duration against S. Marcescens. Vaughan J October 2010 (in-vitro)
21. Smith & Nephew Data on File Report 070304 – Bacterial Barrier Testing (wet-wet) on samples of ALLEVYN Ag Non-Adhesive dressing with a 7 day test duration against MRSA, E. Woodmansey. March 2007 (in-vitro)
22. Data on File 0703013 – Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Ag Adhesive dressing with a 7 day test duration against MRSA. E. Woodmansey, Feb 2007 (in-vitro)
23. ALLEVYN Ag Adhesive dressings: A summary of absorbent capacity and antimicrobial longevity (in-vitro)
24. Memos of 17th June 1993 and 12th October 1999 ALLEVYN Hydrocellular Dressing – Durability Data by D. Quinlan
25. Warriner and Burrell. Infection and the chronic wound: a focus on silver. Advances in skin and wound care. Vol 18, Supp. 1, Oct 2005
26. Lantis J. Gendics, C In vivo effect of sustained-release silver sulphadiazine foam on bioburden and wound closure in infected venous leg ulcers Journal of Wound Care Vol. 20 , no2 , February 2011
27. Kotz P, Fisher J, McCluskey P, Hartwell SD, Dharma H. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds Int Wound J 2009; 6:186–194

ALLEVYN - people

Technology

The ALLEVYN Ag dressings consist of an absorbent hydrocellular foam pad8,9,11,12 held between a highly permeable outer top film and a non-adherent wound contact layer that will not stick to the wound itself10,15,16,17.

Depending on the specific dressing there is a choice of adhesive available to cater for individual patient needs ranging from the gentle soft-gel of ALLEVYN Ag Gentle, the gentle silicone adhesive of ALLEVYN Ag Gentle Border and the secure low allergy18 adhesive of ALLEVYN Ag Adhesive.

ALLEVYN Triple ActionBreathable Top Film

The outer polyurethane top film switches to become more breathable in the presence of exudate 11,12,19.

It also helps to prevent strikethrough and provides an effective barrier to bacteria20,21,22 and minimises the risk of cross contamination.

Highly Absorbent Foam Core

The hydrocellular foam core is highly absorbent8,9,10,11, providing absorption capacity for up to 7 days6,7,23,24.

Non-Adherent Wound Contact Layer 

The wound contact layer will not stick to the wound10,15,16,17 and is available in a range of adhesive types to cater for differing patient needs.

ALLEVYN Ag provides a broad spectrum antimicrobial action2,3 via the inclusion of silver sulfadiazine into the hydrocellular foam pad. Silver is a commonly used antimicrobial agent in woundcare and has been demonstrated to be effective against antibiotic resistant bacteria such as Pseudomonas, MRSA and VRE2,3 for up to 7 days in-vitro3,13,14.

Silver works via a multi-modal action, acting on several different areas of the bacteria to achieve an effective bacterial kill25

ALLEVYN Ag Diagram

Silver acts on several areas of the cell to achieve an effective bacterial kill25. Clinical trials on ALLEVYN Ag have demonstrated its efficacy in patients with Lantis et al observing a significant reduction in bioburden in the wound during the use of ALLEVYN Ag combined with a decrease in the signs and symptoms of infection and a reduction in wound area26.

 

References

1. The clinical and physical properties of ALLEVYN Ag dressings and the moist wound environment
2. Data on File 0707052 – Antimicrobial activity of ALLEVYN Ag dressings against a broad spectrum of wound pathogens using a dynamic shake flask method. July (in-vitro)
3. Smith & Nephew Research Centre Report Ref: RR-WMP07330-10-03. The equivalence of the antimicrobial efficacies of the ALLEVYN Ag foam variants against key wound pathogens. Driffield K, Woodmansey E. Dates 25/03/2009 (in-vitro)
4. Harding KG, Bale S. A randomised clinical study to evaluate and compare the performance of ALLEVYN Adhesive and Tielle dressings in the management of exuding wounds in the community: Smith & Nephew healthcare.
5. Managing diabetic foot lesions with ALLEVYN Heel dressing , Watret L (2000) The Diabetic Foot, 3(1),21-22
6. Data on file report ref: 0711086 – Results from a 7 day volunteer trial evaluating ALLEVYN Gentle dressings in terms of pain on removal, dressing retention and other physical characteristics. A. Bond December 2007
7. Smith & Nephew Medical Ltd. Report Ref: HVT050 Results from an open, prospective, randomised, within volunteer comparison of Dakota and Mepilex Border, Palmer S., & Smith G. 4th December 2008
8. Data on File Reference 0702002, ALLEVYN Ag Adhesive dressing Physical Properties, Daubney L, February 2007 (in-vitro)
9. Data on File Reference 0702001, ALLEVYN Ag Non Adhesive – Physical Properties, L Daubney, February 2007 (in-vitro)
10. Comparing two dressings in the treatment of diabetic foot ulcers, Foster AVM et al (1994), J Wound Care, 3(5), 224-228
11. Smith & Nephew Medical Ltd. Report Ref: DS/08/107/R1b, ALLEVYN Ag Gentle Dressings Physical Properties, Carpenter S. November 2008 (in-vitro)
12. Smith and Nephew Medical Ltd. Report Ref: DS/08/098/R1b, ALLEVYN Ag Gentle Border Dressings Physical Properties, Carpenter S, November 2008 (in-vitro)
13. Data on File 0703014 – Antimicrobial activity of ALLLEVYN Ag Adhesive over 7 days. E. Woodmansey March 2007 (in-vitro)
14. Data on File 0703003 – Antimicrobial activity of ALLEVYN Ag Non-Adhesive over 7 days. E. Woodmansey March 2007 (in-vitro)
15. Avanzi R, Martinelli R, Accardi S, Giraudi C, Peroli P, Rowan S et al. Adhesive hydrocellular dressing vs. hydrocolloid dressing in the treatment of 2nd and 3rd degree pressure ulcers.
16. ALLEVYN Gentle – A 17 day wound healing study in full thickness wounds in minipigs, September 2007
17. ALLEVYN Gentle Border (Dakota) – A 17 day wound healing study in Full Thickness Wounds in Minipigs, October 2008
18. A human repeat insult patch test with adhesive materials. Inveresk Research International Report No. 3524, June 1986
19. Smith & Nephew Data on File Report Comparison of the Permeability of ALLEVYN Non-Adhesive standard and the new ALLEVYN Non-Adhesive written by David Foster and Ana Riel. February 2006 (in-vitro)
20. Smith & Nephew Wound Management, report ref: 070305, Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Gentle, ALLEVYN Gentle Border dressings with 7 day test duration against S. Marcescens. Vaughan J October 2010 (in-vitro)
21. Smith & Nephew Data on File Report 070304 – Bacterial Barrier Testing (wet-wet) on samples of ALLEVYN Ag Non-Adhesive dressing with a 7 day test duration against MRSA, E. Woodmansey. March 2007 (in-vitro)
22. Data on File 0703013 – Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Ag Adhesive dressing with a 7 day test duration against MRSA. E. Woodmansey, Feb 2007 (in-vitro)
23. ALLEVYN Ag Adhesive dressings: A summary of absorbent capacity and antimicrobial longevity (in-vitro)
24. Memos of 17th June 1993 and 12th October 1999 ALLEVYN Hydrocellular Dressing – Durability Data by D. Quinlan
25. Warriner and Burrell. Infection and the chronic wound: a focus on silver. Advances in skin and wound care. Vol 18, Supp. 1, Oct 2005
26. Lantis J. Gendics, C In vivo effect of sustained-release silver sulphadiazine foam on bioburden and wound closure in infected venous leg ulcers Journal of Wound Care Vol. 20 , no2 , February 2011
27. Kotz P, Fisher J, McCluskey P, Hartwell SD, Dharma H. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds Int Wound J 2009; 6:186–194

ALLEVYN - people

Evidence

There is a range of clinical evidence available for ALLEVYN Ag demonstrating its efficacy in patients as well as in vitro. It has been shown to reduce bioburden in the wound, reduce the signs and symptoms of infection and reduce wound area26; all key parameters impacting on patient wellbeing.

Clinical evidence has also shown how ALLEVYN Ag has been positively rated by clinicians in the areas of exudate management, patient comfort and durability27.

Here is a summary of the key pieces of evidence for ALLEVYN Ag. Click through to view further detail.

Variant Author Title
ALLEVYN Ag Non-Adhesive
Lantis J. Gendics, C
Journal of Wound Care Vol. 20 , no2 , February
2011
In vivo effect of sustained-release silver
sulphadiazine foam on bioburden and wound
closure in infected venous leg ulcers
 (PDF - 194kb)
ALLEVYN Ag Kotz P, Fisher J, McCluskey P, Hartwell SD,
Dharma H.
Int Wound J 2009; 6:186–194
Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds (PDF - 183kb)
ALLEVYN Ag Adhesive Kotz P. ALLEVYN Ag Adhesive for a non-progressing ankle wound in a diabetic patient (home care setting) (PDF - 150kb)
ALLEVYN Ag
Heel (Non-Adhesive)
Sanchez Perez et al. ALLEVYN Ag Heel for a critically colonised Stage III pressure ulcer (PDF - 146kb)
ALLEVYN Ag Non Adhesive Mornane C. ALLEVYN Ag Non Adhesive for non-healing leg ulcers (PDF - 152kb)
ALLEVYN Ag Gentle. Monleon Just and Rodriguez Gardia. ALLEVYN Ag Gentle for a fungating breast wound (PDF - 541kb)
ALLEVYN Ag Gentle Border Ivey. ALLEVYN Ag Gentle Border for an infected skin tear. (PDF - 861kb)

 

ALLEVYN - people

FAQs

What is the ALLEVYN Range of Dressings?

The ALLEVYN range of dressings from Smith & Nephew is a comprehensive range of absorbent foam dressings. Trusted with over 25 years of clinical use, the ALLEVYN Range has a history of innovation and putting people first, with a true understanding of the human body and the experience of living with a wound.

ALLEVYN Classics

What products are in the ALLEVYN Classic range?

The ALLEVYN Classic range consists of ALLEVYN Non-Adhesive, ALLEVYN Heel, ALLEVYN Adhesive, ALLEVYN Gentle, ALLEVYN Gentle Border and ALLEVYN Gentle Border Lite.

Why are there several different products within the ALLEVYN Classic range?

The different products in the ALLEVYN Classic range mean that there is a wide range of choice to cater for different patient needs. From those patients requiring a more secure adhesive to those needing a dressing suitable for use under compression, whether the wound is lightly exuding or the skin is fragile there is an ALLEVYN dressing to suit your patient.

How do the dressings in the ALLEVYN Classic range work?

All of the dressings in the ALLEVYN Classic range utilise the unique triple-action technology which consists of a non-adherent wound contact layer1-4, an absorbent foam core2,5-8 and a highly breathable top film2,8-11. This technology is designed to create a moist wound healing environment to keep the wound at the optimal moisture level for wound healing12-17.

The ALLEVYN Ag dressings contain the added benefit of silver suphadiazine within the foam pad to provide a sustained18-20 (in-vitro) and effective20,21 (in-vitro) bacterial kill when an antimicrobial dressing is required.

What type of adhesive are used on the dressings in the ALLEVYN Classics range?

There is a range of adhesion qualities on the different dressings in the ALLEVYN Classic range. ALLEVYN Non-Adhesive has a non-adherent wound contact layer for when no adhesion is required. ALLEVYN Gentle has a low-tack soft gel adhesive designed to provide a gentle helping hand during application of the secondary retention. ALLEVYN Gentle Border and ALLEVYN Gentle Border Lite both have a gentle silicone adhesive across the wound contact layer and border for gentle adhesion with no need for secondary retention, finally ALLEVYN Adhesive provides a secure adhesive for when dressing retention is paramount.

What are the ALLEVYN Classic range of dressings indicated for?

ALLEVYN Dressings have a wide range of indications. Click through to the individual product variant pages for specific indication information.

ALLEVYN Adhesive

ALLEVYN Non Adhesive

ALLEVYN Gentle

ALLEVYN Gentle Border

ALLEVYN Gentle Border Lite

How long can the dressings in the ALLEVYN Classic range be left in place for?

ALLEVYN dressings can be left in place for up to 7 days, except the sacral area where dressings can be left in place for up to 5 days

Which dressings in the ALLEVYN Classic range can be used under compression?

ALLEVYN Non-Adhesive, ALLEVYN Ag Non-Adhesive, ALLEVYN Gentle and ALLEVYN Ag Gentle can all be used under compression

Do the dressings in the ALLEVYN Classic range work in combination with gels?

ALLEVYN dressings can be used in conjunction with INTRASITE Gel for necrotic or sloughy wounds.

Can the dressings in the ALLEVYN Classic range be used with oxidising agents? 

Do not use ALLEVYN dressings with oxidising agents such as hypochlorite solutions (e.g. EUSOL) or hydrogen peroxide, as these can break down the absorbent polyurethane component of the dressing.

What is the silver source in ALLEVYN Ag?

ALLEVYN Ag contains silver sulfadiazine within the foam pad.

What microbes is ALLEVYN Ag effective against?

ALLEVYN Ag is effective against a broad spectrum of bacteria including antibiotic resistant bacteria such as Pseudomonas, Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin Resistant Enterococcus (VRE)20,21 (in-vitro).

Is silver safe?

Silver sulfadiazine has a long history of use in wound care, with the cumulative history of approved clinical use of over 35 years as a Medicinal Product. Post marketing surveillance data collected for SSD show that SSD is effective in preventing and treating infections in burns and other wounds. Please refer to the product leaflet for precautions and contraindications22.

How should ALLEVYN dressings be stored?

ALLEVYN dressings should be stored in a dry place below 25°C / 77°F, away from sunlight.

Can an ALLEVYN dressing dressing be used more than once?

No, ALLEVYN dressing is a single use only product. If used on more than one patient, cross contamination or infection may occur. Opening the dressing pouch compromises the sterile barrier, therefore any unused dressing should not be retained for application at a later date. 

 

References

1. A randomised comparative pilot study to evaluate ALLEVYN hydrocellular dressings and Sorbsan Calcium alginate dressings in the treatment of diabetic foot ulcers, Baker NR, Creevy J. Presented at the 6th Annual Symposium on Advanced Wound Care, San Diego, California, 1993.
2. Bale S, Squires D et al., A comparison of two dressings in pressure sore management. J Wound Care 1997.
3. Data on File: OR/DOF 017.
4. ALLEVYN Gentle - a 17 day wound healing study in full thickness wounds in minipigs. November 2007.
5. Evaluation of a hydrocellular dressing in the management of exuding wounds in the community. Kurring PA et al., (1994). Br J Nurs 3(20) 1049-1053.
6. Data on File: 0709060 (in-vitro).
7. Data on File: 0711080 (in-vitro).
8. Data on File: DS/10/100/R1 (in-vitro).
9. Data on File: 0601003 (in-vitro).
10. Data on File: DS/09/013/R2 (in-vitro).
11. Smith & Nephew data on file report: Comparison of the permeability of ALLEVYN Non-Adhesive standard and new ALLEVYN Non-Adhesive written by David Foster and Anna Rial, Feb 2006 (in-vitro).
12. Data on File: 0601004 (in-vitro).
13. Data on File: 0601003 (in-vitro).
14. Technical Justification: AGB007.
15. Data on File: DS/07/187/R1v2 (in-vitro).
16. Data on File: DS/08/043/R1 (in-vitro).
17. Technical Justification AG0011.
18. Data on File: 0703014 (in-vitro).
19. Data on File: 0703003 (in-vitro).
20. Data on File: RR/WMP07330-10-03 (in-vitro).
21. Data on File: 0707052 (in-vitro).
22. Clinical Expert Report, Flamazine, February 2001.

ALLEVYN - People

Patients

Smith & Nephew is providing information in this site for general educational use only, and does not intend for this to be construed as medical advice or used as a substitute for the advice of your physician. For questions or concerns about a previous or upcoming surgery, Smith & Nephew recommends that you contact your healthcare professional.