Frequently Asked Questions about CADESORB
Q. How often do I need to change CADESORB?
A. CADESORB should be changed every 3 days depending on level of exudate. CADESORB is naturally broken down by the body over time, so any remaining ointment does not cause an issue.
Q. How can I tell when the CADESORB needs changing?
A. The time taken for CADESORB to become saturated and reach its absorbent capacity depends on the rate of exudate from the wound. When this happens the excess exudate will usually be visible as strike-through on the secondary dressing.
The number of dressing changes therefore depends on the levels of exudate present in the wound.
Q. Can I use CADESORB underneath compression therapy?
A. Yes CADESORB can be used under compression therapy
Q. Can I use CADESORB on an infected wound?
A. CADESORB is not indicated for infected wounds. It may be used once the infection has been removed.
Q. How do I remove CADESORB from the wound?
A. Remove the secondary dressing. If it is sticking to the CADESORB or the wound, soak with sterile saline or water. To remove CADESORB from the wound, simply flush it away with sterile saline or water.
If there are any small remnants of CADESORB left in the wound, they will be naturally degraded without causing any delay to healing or systemic reaction.
Q. Can I use a secondary dressing to secure CADESORB to the wound?
A. Yes, you can use an appropriate secondary dressing. OPSITE◊ Post-Op may be appropriate for the lower exuding wounds, whereas ALLEVYN◊ will manage additional exudate levels when this is required.
CADESORB may also be used under compression bandages.
Q. For how long can I use CADESORB?
A. CADESORB may be used until the wound has healed, if there are signs wound healing is progressing and exudate is present.
Q. Is there any risk of putting too much CADESORB into the wound? Would it reduce the pH to a level of acidity that would have a deleterious effect?
A. It is unlikely that too much CADESORB could be applied to the wound. The pKa of CADESORB acid (4.75) dictates that local pH will not drop lower than 1 pH unit either side of this value.
It is recommended however that sufficient be applied to cover the wound area (1 – 2mm) and not leave a large excess surrounding the wound.
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16 Evaluation of model matrix damaging potential of fresh chronic wound fluids and matrix protecting ability of CADESORB™, S&N Data on File Report 0410020.
17 CADESORB Mode of Action. S&N Data on File Report 0412025.
18 Evaluation of model matrix damaging potential of fresh chronic wound fluids and matrix protecting ability of CADESORB and Promogran, S&N Data on File Report 0410021.
19 In-vitro evaluation of the effect of CADESORB and Promogran on the proliferation of three different microorganisms in the presence of serum. S&N Data on File Report 0410019.
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23 A Koerber, J Freise, S Grabbe, J Dissemond. The lowering of pH values in chronic wounds by the application of CADESORB. Poster presentation EWMA Stuttgart 2005.
24 G Robers, A Chumley, R Mani The Wound Milieu in Venous Ulcers – Further Observations. Oral presentation EWMA Stuttgart 2005
25 Matrix protection ability of Cadesorb vs Promogran Smith and Nephew. Data on file 0510001
26 An in vitro assessment of the impact of CADESORB ointment on the antimicrobial properties of various topical antimicrobial agents and dressings (ACTOCOAT◊ Burn, IODOFLEX◊ dressing, Gentalyn Cream, Gentalyn Ointment and FLAMAZINE◊ Cream). Smith and Nephew. Data on file 0505002
27 Anderson L, Iodphore Gel – in-vitro enzymatic hydrolysis of Iodphore Gel and other modified starch gels by endogenous amylase. Micro Chem Development Laboratory AB. 20/06/1979.