Advanced wound management speeds burns healing

A 2012 trial amongst adult patients at the Burns Unit of the the Chris Hani Baragwanath Hospital compared the use Modern Burns Management dressings to conventional dressings.


With 114 patients, the trial was one of the largest randomised, prospective clinical trials in this therapy area worldwide to date. The costs of treating partial thickness burn wounds with advanced burn management products from Smith & Nephew was compared to conventional treatment. 49 patients received Acticoat◊  Biobrane◊ & Versajet™ from the Smith & Nephew burn care portfolio compared to 47 patients who received conventional therapy.


Reducing the human and economic cost of wounds

Independent data released by principal investigator, Dr Adelin Muganza [i]showed that advanced burn management reduced the length of hospital stay by 33% with mean days to healing reduced from 28 to 21 days. The reduction in costs of antibiotics was 88% and there was an overall cost reduction of 20%.

Results of the trial are due to be published in peer reviewed local and international Journals. In the last decade, Smith & Nephew’s Advanced Wound Management Business Unit also provided education to over 800 healthcare professionals - surgeons, registrars, pharmacists, occupational therapists and nurses - on acute, chronic and trauma related effective wound therapy. 

Biobrane product shot

BIOBRANE^ is a temporary biosynthetic skin substitute used on superficial and partial-thickness wounds and donor/sites. International clinical studies [ii, iii, iv, v] have demonstrated that BIOBRANE provides:

  • Decreased length of patient stay
  • Increased speed of healing
  • Decreased pain
  • Increased rate of epithelialisation
  • Increased patient mobility


ACTICOAT◊ is a nanocrystalline silver antimicrobial barrier dressing. Conventional Therapy makes use of silver sulfadiazine and tulle gras daily dressings.  


The  VERSAJET  Hydrosurgery System is a specialized waterjet-powered surgical device designed for procedural efficiency in surgical wound management. Accelerating a hair thin stream of fluid to supersonic speeds, the system enables surgeons to simultaneously grasp, cut and remove damaged tissue and contaminants precisely, without collateral tissue damage associated with current surgical treatment methods.




i. Muganza A. The Costs of Treating Partial Thickness Burn Wounds Treated with Versajet, Biobrane and Acticoat versus Conventional Therapy. Presented at the International Society for Burn Injury, Edinburgh, 2012.

ii. Gerding R.L., Imbembo A.L. & Fratianne RB. Biosynthetic Skin Substitute vs. 1% Silver Sulfadiazine forTreatment of Inpatient Partial-thickness Thermal Burns. The Journal of Trauma. Vol. 28 (8) 1986.

iii. Gerding R.L.,  Emerman C.L., Effron M.,  Lukens T., Imbembo A.L. & Fratianne RB.Outpatient Management of Partial-ThicknessBurns: Biobrane® Versus 1% Silver Sulfadiazine. Presented at the University Association for Emergency Medicine Annual Meeting in Philadelphia, Pennsylvania, May 1987. Also presented at the Geneva Congresson Burns in Geneva, Switzerland, June1987. Sponsored by the International Society Burn Injuries and the World Health Organization.

iv. Greenwood JE, Clausen J, Kavanagh S. Experience With Biobrane: Uses and Caveats for Success. Open Access Journal of Plastic Surgery. June 2009

v. Hankins CL., Tang, XC., Phipps A. Hot beverage burns: An 11-year experience of the Yorkshire Regional Burns Centre. Burns 32 (2006) 87–91.