1. What does 'CUTINOVA' mean?
CUTINOVA is derived from the Latin for 'new skin' (cutis = skin, nova = new).
2. What is selective absorption?
Selective absorption is the process by which CUTINOVA Hydro takes up mainly water from wound exudate, leaving the patient's own growth factors and other natural proteins in the wound 6. Growth factors and proteins are known to be essential agents in wound healing7.
Growth factors control the whole process of healing, from early inflammation, through to wound closure. They are an especially important component of wound fluid and occur naturally in wound exudate 6. Enzymes are necessary for wound debridement and to allow cell movement through tissue, enabling blood vessel growth and re-epithelialisation to occur. Extracellular matrix molecules facilitate cell movement and are essential for the building of new tissue, giving the healing wound structural integrity.
Selective absorption enables CUTINOVA Hydro to concentrate these proteins in the wound fluid rather than taking them up into the dressing. This effect has been demonstrated in vitro, where CUTINOVA Hydro showed an approximate two-fold increase in the concentration of proteins in artificial wound fluid6.
3. Do other dressings selectively absorb?
CUTINOVA Hydro has been proven to significantly increase the concentration of both protein and growth factors in wound fluid. Such concentrations have not been found with any other dressings tested6.
4. What are growth factors?
Growth factors are an especially important component of wound fluid and occur naturally in wound exudate6. They are a type of protein that help tissue repair by encouraging cell division and growth.
5. Why are growth factors important for wound healing?
Growth factors are important for wound healing because they promote cellular division and growth. They are an especially important component of wound fluid and occur naturally in wound exudate6. It is thought that growth factors initiate attraction of cells into the wound and are critical to all aspects of tissue repair7.
6. Does selective absorption help wound healing?
The selective absorption of CUTINOVA Hydro means that the patient's own growth factors are concentrated in the wound. Growth factors help to make a contribution to the rate of wound healing. The process of selective absorption might therefore explain the beneficial effects of CUTINOVA Hydro in the healing of wounds.
7. How do chronic wounds differ from acute wounds in terms of growth factors?
Chronic wounds have lower levels of important growth factors than acute wounds. This could be one of the reasons why chronic wounds can take longer to heal.
8. Can growth factors be put into the wound?
Yes. Growth factors can be applied topically as drugs to stimulate the wound healing process. However, CUTINOVA Hydro concentrates the body's own growth factors.
9. How does CUTINOVA Hydro selectively absorb?
CUTINOVA Hydro is composed of a special polyurethane matrix, which has a high water-absorbing capacity and low protein absorbing capacity. CUTINOVA Hydro is specifically designed to attract and hold water molecules. This means that CUTINOVA Hydro selectively takes up mainly water, leaving the patients own growth factors and other proteins behind in the wound.
10. Will the swelling of CUTINOVA Hydro cause trauma/pressure on the wound bed?
No, CUTINOVA Hydro does not cause pressure on the wound bed because the dressing swells in a controlled manner.
11. Can CUTINOVA Hydro debride?
CUTINOVA Hydro promotes autolytic debridement as it is a moist wound healing dressing. However, Smith & Nephew offers products specifically for wound debridement and wound bed preparation.
12. What is the wear time of CUTINOVA Hydro?
CUTINOVA Hydro can be left in place for up to 7 days, depending on the nature of the wound and the level of exudate.
13. How can the edges be held down to prevent the dressing from lifting when used in awkward places?
CUTINOVA Hydro can be secured in place with OPSITE◊ FLEXIFIX◊ around the edges of the dressing.
14. Can CUTINOVA Hydro be used in conjunction with hydrogels?
CUTINOVA Hydro can be effectively used in combination with hydrogels such as INTRASITE◊ Gel.
15. Does selective absorption mean that the wound is left dry?
No, water is absorbed in a controlled manner to ensure a moist, wound healing environment is always maintained. CUTINOVA Hydro absorbs only excess water, so will not dry out a wound.
16. Is CUTINOVA Hydro occlusive?
No, CUTINOVA Hydro is semi-occlusive. It is waterproof and acts as a bacterial barrier, but allows the transpiration of water vapour, thereby avoiding maceration.
17. Does CUTINOVA Hydro cause any maceration of the peri-wound skin?
CUTINOVA Hydro selectively absorbs excess water from the wound bed which is then bound within the polyurethane matrix. It cannot be squeezed out even under compression. CUTINOVA Hydro has therefore been shown to reduce the risk of maceration1.
18. When should I use CUTINOVA Hydro?
CUTINOVA Hydro is a clean successor to hydrocolloids, as it does not break down in the wound. CUTINOVA Hydro offers the benefits of a hydrocolloid, but also offers a clean, fresh and advanced treatment.
19. What types of wounds can CUTINOVA Hydro be used on?
CUTINOVA Hydro is indicated for use on leg ulcers, pressure ulcers, superficial and partial thickness burns and diabetic foot ulcers, where the surrounding skin is intact.
20. Does CUTINOVA Hydro adhere to the wound?
CUTINOVA Hydro is inherently adhesive, but loses this quality when it comes into contact with wound fluid. For this reason, it does not stick or adhere to the wound (provided that the dressing is used appropriately).
21. Can CUTINOVA Hydro be used under compression?
CUTINOVA Hydro absorbs and retains fluid even under compression. Fluid is absorbed and then bound within the matrix, making it suitable for use under compression.
22. Are any of the ingredients in CUTINOVA Hydro of animal origin?
No. Unlike many hydrocolloids, CUTINOVA Hydro does not involve any ingredients of animal origin.
23. How is CUTINOVA Hydro sterilized?
CUTINOVA Hydro is sterilized using gamma radiation.
24. What is the shelf life of CUTINOVA Hydro?
The shelf life of CUTINOVA Hydro is 5 years.
25. Can CUTINOVA Hydro be re-sterilized?
No. CUTINOVA Hydro should not be re-sterilized because it will become more sticky and adhesive. Each dressing is sterile and for single use only. If the pouch is damaged, the dressing should be discarded and not re-sterilized.
For References see the Abstracts tab