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A randomised comparative pilot...

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Baker NR, Creevy J. A randomised comparative pilot study to evaluate Allevyn* Hydrocellular dressings and Sorbsan Calcium-Alginate dressings in the treatment of diabetic foot ulcers. Smith & Nephew Poster Presentation. Data on File.

 

Type of Study: Randomised Controlled Trial (Pilot Study)

 

Type of Wound: Diabetic Foot Ulcers

 

Abstract

Nineteen patients with neuropathic foot ulcers were randomised to receive treatment with Allevyn or an alginate dressing.


Patients were assessed over a 12 week period,or until the ulcer healed.


Assessment was made in the Diabetic Foot Clinic at weekly intervals. If required, intermediate dressing changes were performed in the community setting.


The primary objective of the study was to assess the effectiveness of Allevyn compared to an alginate dressing.


Time to healing was compared between the two treatment groups using Cox's proportional Hazards Model. Absorbency, non-adherence and ease of removal were statistically analysed.


Key Findings

  • After 12 weeks 90% of the ulcers managed with Allevyn had healed compared to only44% in the alginate group.
  • The rate of healing was significantly faster with Allevyn (p=0.027). The median time to healing was 28 days with Allevyn and greater than 84days with the alginate dressing.
  • Allevyn Hydrocellular was significantly more absorbent than the alginate dressing (p= 0.001).
  • The Allevyn dressings were less adherent to the wound and were significantly easier to remove (p=0.011) than the alginate dressing.