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ALLEVYN Ag

Advanced Foam Wound Dressings

ALLEVYN Ag

Product Information

ALLEVYN AG

Wound infection can significantly compromise patient wellbeing and place heavy burdens on healthcare economies. The ALLEVYN Ag dressings have been designed to combine the essential qualities of the ALLEVYN range with the added antimicrobial activity of silver.

The unique tri-layer construction of the dressings enable optimal fluid handling to support moist wound healing1 and the addition of SSD to the foam pad provides a broad spectrum bacterial kill in-vitro2,3. The dressings are comfortable for patients, conform to body contours and are easy to apply and remove4,5,6,7.

The ALLEVYN Ag range is available as:

ALLEVYN Ag AdhesiveALLEVYN Ag Adhesive

A highly absorbent8 secure antimicrobial dressing that is also available in a sacral shape for this area that is at high risk of contamination

 

ALLEVYN Ag Adhesive Size and Ordering Information

Size

Pieces per carton

 

7.5cm x 7.5cm

10

 

10cm x 10cm

10

 

12.5cm x 12.5cm

10

 

17.5cm x 17.5cm

10

 

Sacrum 17cm x 17cm

10

 

Sacrum 22cm x 22cm

10

 

 

ALLEVYN Ag Non-AdhesiveALLEVYN Ag Non-Adhesive

A highly absorbent9 non-adherent10 antimicrobial dressing suitable for compromised skin that can be cut to suit the patient

ALLEVYN Ag Non-Adhesive Size and Ordering Information

Size

Pieces per carton

 

5cm x 5cm

10

 

10cm x 10cm

10

 

10cm x 20cm

10

 

15cm x 15cm

10

 

20cm x 20cm

10

 

Heel

5

 

 

ALLEVYN Ag GentleALLEVYN Ag Gentle

A highly absorbent11 antimicrobial dressing with a soft gel gentle adhesive to enable easy application6 under secondary retention including compression.

ALLEVYN Ag Gentle Size and Ordering Information

Size

Pieces per carton

 

5cm x 5cm

10

 

10cm x 10cm

10

 

10cm x 20cm

10

 

15cm x 15cm

10

 

20cm x 20cm

10

 

 

ALLEVYN Ag Gentle BorderALLEVYN Ag Gentle Border

A highly absorbent12 antimicrobial dressing with a gentle silicone adhesive, the ideal one step dressing for use on fragile skin7.

ALLEVYN Ag Gentle Border Size and Ordering Information

Size

Pieces per carton

 

7.5cm x 7.5cm

10

 

10cm x 10cm

10

 

12.5cm x 12.5cm

10

 

17.5cm x 17.5cm

10

 

 

All of the ALLEVYN Ag dressings combine the physical qualities of the ALLEVYN tri-layer construction with the antimicrobial activity of SSD. Proven in vitro against a broad spectrum of bacteria including antibiotic resistant bacteria such as Pseudomonas, Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin Resistant Enterococcus (VRE)2,3 the ALLEVYN Ag range provides a sustained action with antimicrobial properties remaining effective for up to 7 days in-vitro3,13,14.

The ALLEVYN Ag dressings are indicated for:

  • Shallow, granulating wounds
  • Chronic and acute exudative wounds
  • Full and partial thickness wounds such as pressure ulcers, leg ulcers and diabetic foot ulcers
  • Infected wounds
  • Malignant wounds
  • Surgically dehisced wounds
  • First and second degree burns
  • Donor sites
  • Fungating wounds

 

References

1. The clinical and physical properties of ALLEVYN Ag dressings and the moist wound environment
2. Data on File 0707052 – Antimicrobial activity of ALLEVYN Ag dressings against a broad spectrum of wound pathogens using a dynamic shake flask method. July
3. Smith & Nephew Research Centre Report Ref: RR-WMP07330-10-03. The equivalence of the antimicrobial efficacies of the ALLEVYN Ag foam variants against key wound pathogens. Driffield K, Woodmansey E. Dates 25/03/2009
4. Harding KG, Bale S. A randomised clinical study to evaluate and compare the performance of ALLEVYN Adhesive and Tielle dressings in the management of exuding wounds in the community: Smith & Nephew healthcare.
5. Managing diabetic foot lesions with ALLEVYN Heel dressing , Watret L (2000) The Diabetic Foot, 3(1),21-22
6. Data on file report ref: 0711086 – Results from a 7 day volunteer trial evaluating ALLEVYN Gentle dressings in terms of pain on removal, dressing retention and other physical characteristics. A. Bond December 2007
7. Smith & Nephew Medical Ltd. Report Ref: HVT050 Results from an open, prospective, randomised, within volunteer comparison of Dakota and Mepilex Border, Palmer S., & Smith G. 4th December 2008
8. Data on File Reference 0702002, ALLEVYN Ag Adhesive dressing Physical Properties, Daubney L, February 2007
9. Data on File Reference 0702001, ALLEVYN Ag Non Adhesive – Physical Properties, L Daubney, February 2007
10. Comparing two dressings in the treatment of diabetic foot ulcers, Foster AVM et al (1994), J Wound Care, 3(5), 224-228
11. Smith & Nephew Medical Ltd. Report Ref: DS/08/107/R1b, ALLEVYN Ag Gentle Dressings Physical Properties, Carpenter S. November 2008
12. Smith and Nephew Medical Ltd. Report Ref: DS/08/098/R1b, ALLEVYN Ag Gentle Border Dressings Physical Properties, Carpenter S, November 2008
13. Data on File 0703014 – Antimicrobial activity of ALLLEVYN Ag Adhesive over 7 days. E. Woodmansey March 2007
14. Data on File 0703003 – Antimicrobial activity of ALLEVYN Ag Non-Adhesive over 7 days. E. Woodmansey March 2007
15. Avanzi R, Martinelli R, Accardi S, Giraudi C, Peroli P, Rowan S et al. Adhesive hydrocellular dressing vs. hydrocolloid dressing in the treatment of 2nd and 3rd degree pressure ulcers.
16. ALLEVYN Gentle – A 17 day wound healing study in full thickness wounds in minipigs, September 2007
17. ALLEVYN Gentle Border (Dakota) – A 17 day wound healing study in Full Thickness Wounds in Minipigs, October 2008
18. A human repeat insult patch test with adhesive materials. Inveresk Research International Report No. 3524, June 1986
19. Smith & Nephew Data on File Report Comparison of the Permeability of ALLEVYN Non-Adhesive standard and the new ALLEVYN Non-Adhesive written by David Foster and Ana Riel. February 2006
20. Smith & Nephew Wound Management, report ref: 070305, Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Gentle, ALLEVYN Gentle Border dressings with 7 day test duration against S. Marcescens. Vaughan J October 2010
21. Smith & Nephew Data on File Report 070304 – Bacterial Barrier Testing (wet-wet) on samples of ALLEVYN Ag Non-Adhesive dressing with a 7 day test duration against MRSA, E. Woodmansey. March 2007
22. Data on File 0703013 – Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Ag Adhesive dressing with a 7 day test duration against MRSA. E. Woodmansey, Feb 2007
23. ALLEVYN Ag Adhesive dressings: A summary of absorbent capacity and antimicrobial longevity.
24. Memo’s of 17th June 1993 and 12th October 1999 ALLEVYN Hydrocellular Dressing – Durability Data by D. Quinlan
25. Warriner and Burrell. Infection and the chronic wound: a focus on silver. Advances in skin and wound care. Vol 18, Supp. 1, Oct 2005
26. Lantis J. Gendics, C In vivo effect of sustained-release silver sulphadiazine foam on bioburden and wound closure in infected venous leg ulcers Journal of Wound Care Vol. 20 , no2 , February 2011
27. Kotz P, Fisher J, McCluskey P, Hartwell SD, Dharma H. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds Int Wound J 2009; 6:186–194

ALLEVYN - people

Technology

The ALLEVYN Ag dressings consist of an absorbent hydrocellular foam pad8,9,11,12 held between a highly permeable outer top film and a non-adherent wound contact layer that will not stick to the wound itself10,15,16,17.

Depending on the specific dressing there is a choice of adhesive available to cater for individual patient needs ranging from the gentle soft-gel of ALLEVYN Ag Gentle, the gentle silicone adhesive of ALLEVYN Ag Gentle Border and the secure low allergy18 adhesive of ALLEVYN Ag Adhesive.

ALLEVYN Triple ActionBreathable Top Film

The outer polyurethane top film switches to become more breathable in the presence of exudate 11,12,19.

It also helps to prevent strikethrough and provides an effective barrier to bacteria20,21,22 and minimises the risk of cross contamination.

Highly Absorbent Foam Core

The hydrocellular foam core is highly absorbent8,9,10,11, providing absorption capacity for up to 7 days6,7,23,24.

Non-Adherent Wound Contact Layer 

The wound contact layer will not stick to the wound10,15,16,17 and is available in a range of adhesive types to cater for differing patient needs.

ALLEVYN Ag provides a broad spectrum antimicrobial action2,3 via the inclusion of silver sulfadiazine into the hydrocellular foam pad. Silver is a commonly used antimicrobial agent in woundcare and has been demonstrated to be effective against antibiotic resistant bacteria such as Pseudomonas, MRSA and VRE2,3 for up to 7 days in-vitro3,13,14.

Silver works via a multi-modal action, acting on several different areas of the bacteria to achieve an effective bacterial kill25

ALLEVYN Ag Diagram

Silver acts on several areas of the cell to achieve an effective bacterial kill25. Clinical trials on ALLEVYN Ag have demonstrated its efficacy in patients with Lantis et al observing a significant reduction in bioburden in the wound during the use of ALLEVYN Ag combined with a decrease in the signs and symptoms of infection and a reduction in wound area26.

 

References

1. The clinical and physical properties of ALLEVYN Ag dressings and the moist wound environment
2. Data on File 0707052 – Antimicrobial activity of ALLEVYN Ag dressings against a broad spectrum of wound pathogens using a dynamic shake flask method. July
3. Smith & Nephew Research Centre Report Ref: RR-WMP07330-10-03. The equivalence of the antimicrobial efficacies of the ALLEVYN Ag foam variants against key wound pathogens. Driffield K, Woodmansey E. Dates 25/03/2009
4. Harding KG, Bale S. A randomised clinical study to evaluate and compare the performance of ALLEVYN Adhesive and Tielle dressings in the management of exuding wounds in the community: Smith & Nephew healthcare.
5. Managing diabetic foot lesions with ALLEVYN Heel dressing , Watret L (2000) The Diabetic Foot, 3(1),21-22
6. Data on file report ref: 0711086 – Results from a 7 day volunteer trial evaluating ALLEVYN Gentle dressings in terms of pain on removal, dressing retention and other physical characteristics. A. Bond December 2007
7. Smith & Nephew Medical Ltd. Report Ref: HVT050 Results from an open, prospective, randomised, within volunteer comparison of Dakota and Mepilex Border, Palmer S., & Smith G. 4th December 2008
8. Data on File Reference 0702002, ALLEVYN Ag Adhesive dressing Physical Properties, Daubney L, February 2007
9. Data on File Reference 0702001, ALLEVYN Ag Non Adhesive – Physical Properties, L Daubney, February 2007
10. Comparing two dressings in the treatment of diabetic foot ulcers, Foster AVM et al (1994), J Wound Care, 3(5), 224-228
11. Smith & Nephew Medical Ltd. Report Ref: DS/08/107/R1b, ALLEVYN Ag Gentle Dressings Physical Properties, Carpenter S. November 2008
12. Smith and Nephew Medical Ltd. Report Ref: DS/08/098/R1b, ALLEVYN Ag Gentle Border Dressings Physical Properties, Carpenter S, November 2008
13. Data on File 0703014 – Antimicrobial activity of ALLLEVYN Ag Adhesive over 7 days. E. Woodmansey March 2007
14. Data on File 0703003 – Antimicrobial activity of ALLEVYN Ag Non-Adhesive over 7 days. E. Woodmansey March 2007
15. Avanzi R, Martinelli R, Accardi S, Giraudi C, Peroli P, Rowan S et al. Adhesive hydrocellular dressing vs. hydrocolloid dressing in the treatment of 2nd and 3rd degree pressure ulcers.
16. ALLEVYN Gentle – A 17 day wound healing study in full thickness wounds in minipigs, September 2007
17. ALLEVYN Gentle Border (Dakota) – A 17 day wound healing study in Full Thickness Wounds in Minipigs, October 2008
18. A human repeat insult patch test with adhesive materials. Inveresk Research International Report No. 3524, June 1986
19. Smith & Nephew Data on File Report Comparison of the Permeability of ALLEVYN Non-Adhesive standard and the new ALLEVYN Non-Adhesive written by David Foster and Ana Riel. February 2006
20. Smith & Nephew Wound Management, report ref: 070305, Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Gentle, ALLEVYN Gentle Border dressings with 7 day test duration against S. Marcescens. Vaughan J October 2010
21. Smith & Nephew Data on File Report 070304 – Bacterial Barrier Testing (wet-wet) on samples of ALLEVYN Ag Non-Adhesive dressing with a 7 day test duration against MRSA, E. Woodmansey. March 2007
22. Data on File 0703013 – Bacterial Barrier testing (wet-wet) on samples of ALLEVYN Ag Adhesive dressing with a 7 day test duration against MRSA. E. Woodmansey, Feb 2007
23. ALLEVYN Ag Adhesive dressings: A summary of absorbent capacity and antimicrobial longevity.
24. Memo’s of 17th June 1993 and 12th October 1999 ALLEVYN Hydrocellular Dressing – Durability Data by D. Quinlan
25. Warriner and Burrell. Infection and the chronic wound: a focus on silver. Advances in skin and wound care. Vol 18, Supp. 1, Oct 2005
26. Lantis J. Gendics, C In vivo effect of sustained-release silver sulphadiazine foam on bioburden and wound closure in infected venous leg ulcers Journal of Wound Care Vol. 20 , no2 , February 2011
27. Kotz P, Fisher J, McCluskey P, Hartwell SD, Dharma H. Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds Int Wound J 2009; 6:186–194

ALLEVYN - people

Evidence

There is a range of clinical evidence available for ALLEVYN Ag demonstrating its efficacy in patients as well as in vitro. It has been shown to reduce bioburden in the wound, reduce the signs and symptoms of infection and reduce wound area26; all key parameters impacting on patient wellbeing.

Clinical evidence has also shown how ALLEVYN Ag has been positively rated by clinicians in the areas of exudate management, patient comfort and durability27.

Here is a summary of the key pieces of evidence for ALLEVYN Ag. Click through to view further detail.

Variant Author Title
  Lantis J. Gendics, C
Journal of Wound Care Vol. 20 , no2 , February
2011
In vivo effect of sustained-release silver
sulphadiazine foam on bioburden and wound
closure in infected venous leg ulcers
 (PDF - 194kb)
ALLEVYN Ag Kotz P, Fisher J, McCluskey P, Hartwell SD,
Dharma H.
Int Wound J 2009; 6:186–194
Use of a new silver barrier dressing, ALLEVYN Ag in exuding chronic wounds (PDF - 183kb)
ALLEVYN Ag Adhesive Kotz P. ALLEVYN Ag Adhesive for a non-progressing ankle wound in a diabetic patient (home care setting) (PDF - 150kb)
ALLEVYN Ag
Heel (Non-Adhesive)
Sanchez Perez et al. ALLEVYN Ag Heel for a critically colonised Stage III pressure ulcer (PDF - 146kb)
ALLEVYN Ag Non Adhesive Mornane C. ALLEVYN Ag Non Adhesive for non-healing leg ulcers (PDF - 152kb)
ALLEVYN Ag Gentle. Monleon Just and Rodriguez Gardia. ALLEVYN Ag Gentle for a fungating breast wound (PDF - 541kb)
ALLEVYN Ag Gentle Border Ivey. ALLEVYN Ag Gentle Border for an infected skin tear. (PDF - 861kb)

 

ALLEVYN - people

Instructions for Use

ALLEVYN Ag Adhesive

1. Cleanse the wound in accordance with local clinical protocol.
2. Select an appropriate dressing size. ALLEVYN Ag Adhesive can be cut to fit awkward areas.
3. Prepare and clean the skin surrounding the wound area and remove excess moisture. Any excess hair should be clipped to ensure close approximation to the wound.
4. Remove ALLEVYN Ag Adhesive from the pack using a clean technique
5. Remove one of the protector films from ALLEVYN Ag Adhesive and anchor the adhesive side of the dressing to the skin.
6. Remove the remaining protector film and smooth the dressing over the remainder of the wound without stretching, ensuring there are no creases. The pad area of the dressing must be adhered across the entire surface of the wound.
7. If the dressing has been cut, ensure any exposed foam areas are covered with an appropriate film dressing taking care not to cover the entire dressing
8. When positioning ALLEVYN Ag Sacrum dressing place the narrow end of the dressing a minimum of 2cm above the anal sphincter, then smooth the dressing over the sacrum.


Frequency of Change

During the early stages of wound management ALLEVYN Ag Adhesive should be inspected according to local clinical protocol. Where the product is used on infected wounds the infection should be inspected and treated as per local clinical protocol.

Dressings can be left in place, undisturbed, for up to 7 days depending on the condition of the wound and the surrounding skin or until exudate is visible and approaches to within 2cm / 3/16in. of the edge of the dressing pad, whichever is sooner. Local clinical protocols should also be taken into consideration.

ALLEVYN When to Change 1
No need to change 



ALLEVYN When to Change 1
No need to change 



ALLEVYN When to Change 1
Exudate within 2cm of the edge of the pad requires changing



If dressings are applied to the sacral area, they may be left in place for up to 5 days, however, due to the increased potential for contamination and infection in this area, increased monitoring of dressing adherence may be required as per local clinical protocols.

The decision of when to change should be dependent upon clinical assessment and local protocols should also be taken into consideration.


Dressing Removal

To remove ALLEVYN Ag Adhesive, lift one edge of the dressing and slowly peel back until completely removed from the wound. Sacral dressings should be removed from the top edge down towards the anus to minimise the potential for faecal contamination.

ALLEVYN Ag Non-Adhesive

1. Cleanse the wound in accordance with local clinical protocol.
2. Select an appropriate dressing size. ALLEVYN Ag Non-Adhesive can be cut to fit awkward areas. When used under compression therapy, the dressing must be cut to the size of the wound.
3. Prepare and clean the skin surrounding the wound area and remove excess moisture.
Any excess hair should be clipped to ensure close approximation to the wound.
4. Remove ALLEVYN Ag Non-Adhesive from the pack using a clean technique.
5. Apply the white face to the wound ensuring good contact and secure with a dressing retention sheet, (e.g. OPSITE Flexifix or OPSITE Flexifix Gentle), tape or bandage.


Frequency of Change

During the early stages of wound Management, ALLEVYN Ag Non-Adhesive should be inspected according to local clinical protocol. Where the product is used on infected wounds the infection should be inspected and treated as per local clinical protocol.

Dressings can be left in place undisturbed for up to 7 days, or until exudate is visible and approaches 1.5cm from the edge of the dressing, whichever is sooner.

If dressings are applied to the sacral area, they may be left in place for up to 5 days, however, due to the increased potential for contamination and infection in this area, increased monitoring of dressing adherence may be required as per local clinical protocols.
The decision of when to change should be dependent upon clinical assessment and local protocols should also be taken into consideration.

The decision of when to change should be dependent upon clinical assessment and local protocols should also be taken into consideration.


Dressing Removal

To remove ALLEVYN Ag Non-Adhesive remove the retention dressing or bandage and lift the dressing away from the wound.

ALLEVYN Ag Gentle 

1. Cleanse the wound in accordance with local clinical protocol.
2. Select an appropriate dressing size. ALLEVYN Ag Gentle can be cut to fit awkward areas. Always use a clean technique when cutting the dressing.
3. Prepare and clean the skin surrounding the wound area and remove excess moisture.
Any excess hair should be clipped to ensure close approximation to the wound.
4. Using a clean technique remove the protector material from ALLEVYN Ag Gentle and apply the adherent side to the wound ensuring good contact all the way around and secure with secondary retention e.g. OPSITE Flexifix, OPSITE Flexifix Gentle, tape or bandage. ALLEVYN Ag Gentle can be lifted and repositioned on application without losing its adherent properties.
5. ALLEVYN Ag Gentle can be used in combination with other methods of treatment e.g. compression therapy, under the supervision of a healthcare professional. When used under compression the dressing must be cut to the size of the wound without overlapping on to surrounding skin and care should be taken to ensure that the dressing is adhered in position before compression bandages are applied.
6. If the dressing has been cut, ensure any exposed foam areas are covered with an appropriate film dressing taking care not to cover the entire dressing.


Frequency of Change

 During the early stages of wound management ALLEVYN Ag Gentle should be inspected according to local clinical protocol. Where the product is used on infected wounds the infection should be inspected and treated as per local clinical protocol.

Dressings can be left in place undisturbed for up to 7 days, or until exudate is visible and approaches 1.5cm from the dressing edge, whichever is sooner.

If dressings are applied to the sacral area, they may be left in place for up to 5 days, however, due to the increased potential for contamination and infection in this area, increased monitoring of dressing adherence may be required as per local clinical protocols.

The decision of when to change should be dependent upon clinical assessment and local protocols should also be taken into consideration.


Dressing Removal

 To remove ALLEVYN Ag Gentle, remove the secondary retention and lift the dressing away from the wound.

ALLEVYN Ag Gentle Border

1. Cleanse the wound in accordance with local clinical protocol.
2. Select an appropriate dressing size. ALLEVYN Ag Gentle Border can be cut, to dress wounds on the heels, elbows and other awkward areas. Always use a clean technique when cutting the dressing.
3. Prepare and clean the skin surrounding the wound area and remove excess moisture. Any excess hair should be clipped to ensure close approximation to the wound.
4. Using a clean technique remove one of the protector films from ALLEVYN Ag Gentle Border and anchor the adhesive side of the dressing to the skin.
5. Remove the remaining protector film and smooth the dressing over the remainder of the wound without stretching, ensuring there are no creases. The pad area of the dressing must be adhered across the entire surface of the wound. ALLEVYN Ag Gentle Border can be lifted and repositioned without losing its adherent properties.
6. If the dressing has been cut ensure any exposed foam areas are covered with an appropriate film dressing taking care not to cover the entire dressing.


Frequency of Change

During the early stages of wound management ALLEVYN Ag Gentle Border should be inspected according to local clinical protocol. Where the product is used on infected wounds the infection should be inspected and treated as per local clinical protocol.

Dressings can be left in place, undisturbed, for up to 7 days, depending on the condition of the wound and the surrounding skin or until exudate is visible and approaches to within 2cm of the edge of the dressing pad, whichever is sooner.

If dressings are applied to the sacral area, they may be left in place for up to 5 days, however, due to the increased potential for contamination and infection in this area, increased monitoring of dressing adherence may be required as per local clinical protocols.

The decision of when to change should be dependent upon clinical assessment and local protocols should also be taken into consideration.


Dressing Removal

To remove ALLEVYN Ag Gentle Border, lift one edge of the dressing and slowly peel back until completely removed from the wound. Sacral dressings should be removed from the top

ALLEVYN - people