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Ratcliff, CR: IGel to promote

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Ratcliff, C, R. Intrasite Gel to Promote Wound Healing from Necrosis. The Cancer Bulletin 1991; 43: 1:85-86

Localised carcinomas of the cervix are usually responsive to radiotherapy. Those that are not are considered secondary to the bulk of the tumour at the beginning of radiotherapy. In an attempt to reduce the tumour volume intra-arterial chemotherapy, which delivers large concentrations of chemotherapeutic agents through the arteries supplying the malignant area, may be given prior to radiotherapy to patients with advanced localised disease. Necrosis is occasionally seen as a complication of the intra-arterial therapy or the radiotherapy and presents a challenge in terms of clinical management of the wound. The use of a hydrogel to promote healing in such a case is reviewed in this article